Cardiovascular effects of overt and subclinical hyperthyroidism: focus on differentiated thyroid cancer

Thyroid hormone stimulates cardiac inotropy and chronotropy via direct genomic non-genomic mechanisms. Hyperthyroidism magnifies these effects, resulting in an increase heart rate, ejection fraction blood volume. also affects thrombogenesis this may be linked to a probable tendency toward thrombosis patients with hyperthyroidism. Patients hyperthyroidism are therefore at higher risk for atrial fibrillation, failure cardiovascular mortality. Similarly, TSH suppressive therapy differentiated thyroid cancer is associated increased risk. In review, we present the latest insights on effects of suppression treatment cancer. Finally, will show new clinical data how implement knowledge into practice preventive medicine.